After so, So, SO much screwing around with RAID box's, and OS X's, and Servers, and Mac Pro's; I've settled on one Quad 3Ghz Mac1,1, running El Capitan with Server 5.1.5 doing Caching, 'and some stuff', and one Quad 2.66Ghz Mac1,1 running Lion and Server 1.5.0 (The version of Server that runs on Lion - which is the last OS X that will run unmolested on a Mac Pro Mac1,1) - performing File Serving of the (4) Drobo Pro's connected via iSCSI (Butchered for the Drobo Box), and the last version of Drobo Dashboard that would run on a G5 - even though this is an Intel machine. XBench gives the Drobo Pro's a decent sequential Read/Write performance for large block transfers, except for small block read. The small block Write sequential performance is almost certainly due to buffering and thin provisioning - no surprise as that's why buffering with thin provisioning were designed like that. Random performance is what it always is with Hard Drives - a bummer. All in all, these out of date Drobo's are quite suitable for rsync and Time Machine targets; precisely what they're suppose to be.
Higher performance requirements are still well met by the ReadyNAS NAS/SAN machines.